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Merck

MYOC

myocilin, trabecular meshwork inducible glucocorticoid response

Synonymes:
GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4653) Summary: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]
  • Mouse(17926) myocilin
  • Rat(81523) myocilin, trabecular meshwork inducible glucocorticoid response
  • Zebrafish(548602) myocilin
  • chicken(424391) myocilin, trabecular meshwork inducible glucocorticoid response
  • dog(490344) myocilin, trabecular meshwork inducible glucocorticoid response
  • domestic cat(101087632) myocilin, trabecular meshwork inducible glucocorticoid response
  • cow(281342) myocilin, trabecular meshwork inducible glucocorticoid response
  • Horse(100059848) myocilin, trabecular meshwork inducible glucocorticoid response
  • sheep(101105836) myocilin, trabecular meshwork inducible glucocorticoid response
  • Domestic Rabbit(100008897) myocilin, trabecular meshwork inducible glucocorticoid response
  • naked mole-rat(101705679) myocilin, trabecular meshwork inducible glucocorticoid response
  • domestic guinea pig(100721171) myocilin, trabecular meshwork inducible glucocorticoid response

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Myocilin (NT) Antibody, clone 7.1, clone 7.1, from mouse,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
Anti-MYOC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-MYOC antibody produced in mouse, clone 4F8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-MYOC antibody produced in mouse, clone 2B4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MYOC,
Espèce(s)
human