MYC
v-myc avian myelocytomatosis viral oncogene homolog
Synonymes:
MRTL, MYCC, bHLHe39, c-Myc
Espèce(s):
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
ID UniProtKB:
ID du gène:
- Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
- Mouse(17869) myelocytomatosis oncogene
- Rat(24577) myelocytomatosis oncogene
- chicken(420332) v-myc myelocytomatosis viral oncogene homolog
- dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
- cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
- Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
- sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
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ELISA
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Espèces réactives
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anticorps monoclonal de souris anti-c-Myc antibody produced in mouse, clone 9E10, purified from hybridoma cell culture,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anticorps anti-étiquette Myc, clone 4A6, clone 4A6, Upstate®, from mouse,
Espèces réactives
human
Application
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-c-Myc antibody produced in rabbit, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
Anti-Myc Tag Antibody, clone 9E10, Alexa Fluor™ 488 conjugate, clone 9E10, Upstate®, from mouse,
Espèces réactives
all
Application
immunocytochemistry
western blot
western blot
Proteins
Référence du produit
Description
Espèce(s)
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human