Accéder au contenu
Merck

MAP3K14

mitogen-activated protein kinase kinase kinase 14

Synonymes:
FTDCR1B, HS, HSNIK, NIK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9020) Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
  • Mouse(53859) mitogen-activated protein kinase kinase kinase 14
  • Rat(360640) mitogen-activated protein kinase kinase kinase 14
  • chicken(419964) mitogen-activated protein kinase kinase kinase 14
  • domestic cat(101083468) mitogen-activated protein kinase kinase kinase 14
  • Horse(100050140) mitogen-activated protein kinase kinase kinase 14
  • cow(508367) mitogen-activated protein kinase kinase kinase 14
  • dog(490926) mitogen-activated protein kinase kinase kinase 14
  • Domestic Rabbit(100351032) mitogen-activated protein kinase kinase kinase 14
  • naked mole-rat(101703313) mitogen-activated protein kinase kinase kinase 14
  • domestic guinea pig(100719582) mitogen-activated protein kinase kinase kinase 14
  • sheep(101118799) mitogen-activated protein kinase kinase kinase 14

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-NIK (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
Anti-MAP3K14 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
proximity ligation assay

western blot
Anti-MAP3K14 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit
Application
western blot
Anti-NIK Antibody, CT, Chemicon®, from rabbit,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
MAP3K14(NIK) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MAP3K14,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Map3k14,
Espèce(s)
mouse