MAP2K7
mitogen-activated protein kinase kinase 7
Synonymes:
Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK-4, SAPKK4
Espèce(s):
Human MAP2K7 (5609), Mouse Map2k7 (26400), Rat Map2k7 (363855), Zebrafish map2k7 (560913), dog MAP2K7 (485004), cow MAP2K7 (787278), domestic cat MAP2K7 (101095157), sheep MAP2K7 (100302082), naked mole-rat Map2k7 (101710666), domestic guinea pig Map2k7 (100731057)
ID UniProtKB:
ID du gène:
- Human(5609) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008]
- Mouse(26400) mitogen-activated protein kinase kinase 7
- Rat(363855) mitogen activated protein kinase kinase 7
- Zebrafish(560913) mitogen-activated protein kinase kinase 7
- dog(485004) mitogen-activated protein kinase kinase 7
- cow(787278) mitogen-activated protein kinase kinase 7
- domestic cat(101095157) mitogen-activated protein kinase kinase 7
- sheep(100302082) mitogen-activated protein kinase kinase 7
- naked mole-rat(101710666) mitogen-activated protein kinase kinase 7
- domestic guinea pig(100731057) mitogen-activated protein kinase kinase 7
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-phospho-MKK7/SKK4 (Thr275/Ser277) Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-MAP2K7 (pSer271) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-MAP2K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-MAP2K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Monoclonal Anti-MAP2K7 antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)
MKK7β1 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human MKK7β1, amino acids 2-end. For use in Kinase Assays.,
Espèce(s)
human
MKK7β1 Protein, inactive, 50 g, Unactive, N-terminal GST-tagged, recombinant, human MKK7β1 amino acids 2-end, for use in Kinase Assays.,
Espèce(s)
human