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Merck

KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5

Synonymes:
Kv7.5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(56479) Summary: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(226922) potassium voltage-gated channel, subfamily Q, member 5
  • Rat(259273) potassium voltage-gated channel, KQT-like subfamily, member 5
  • chicken(421866) potassium voltage-gated channel, KQT-like subfamily, member 5
  • cow(613605) potassium voltage-gated channel, KQT-like subfamily, member 5
  • Horse(100071357) potassium voltage-gated channel, KQT-like subfamily, member 5
  • domestic cat(101092113) potassium voltage-gated channel, KQT-like subfamily, member 5
  • dog(474965) potassium voltage-gated channel, KQT-like subfamily, member 5
  • domestic guinea pig(100721474) potassium voltage-gated channel, KQT-like subfamily, member 5
  • naked mole-rat(101704304) potassium voltage-gated channel, KQT-like subfamily, member 5
  • sheep(100174987) potassium voltage-gated channel, KQT-like subfamily, member 5
  • Domestic Rabbit(100328657) potassium voltage-gated channel, KQT-like subfamily, member 5

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Small Molecule - Activator

Référence du produit
Description
Espèce(s)
BMS 204352, ≥98% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Potassium Channel KCNQ5 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
canine, chimpanzee, feline, giant panda, human, rat, rhesus macaque
Application
immunohistochemistry
western blot
Anti-KCNQ5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-KCNQ5 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Retigabine, analytical standard,
Espèce(s)
human
Guanidine hydrochloride, for molecular biology, ≥99%,
Espèce(s)
human
Guanidine hydrochloride, ≥98%,
Espèce(s)
human
Guanidine hydrochloride, organic base and chaeotropic agent, ≥99% (titration),
Espèce(s)
human
Guanidine hydrochloride, ,
Espèce(s)
human

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
N-éthylmaléimide, crystalline, ≥98% (HPLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human KCNQ5,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Kcnq5,
Espèce(s)
mouse