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Merck

ITGB3

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Synonymes:
BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3690) Summary: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
  • Mouse(16416) integrin beta 3
  • Rat(29302) integrin, beta 3
  • sheep(100423047) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • domestic guinea pig(100731365) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • naked mole-rat(101715910) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • chicken(374209) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • domestic cat(101092159) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • cow(282642) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • Horse(100009709) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • dog(403788) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Gly-Arg-Gly-Asp-Ser, ≥97% (HPLC),
Espèce(s)
human
Arg-Gly-Asp-Ser, ≥95% (HPLC),
Espèce(s)
mouse, human
Acetylsalicylic acid, ≥99.0%,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62, clone ab62, from mouse,
Espèces réactives
human
Application
flow cytometry
western blot
Monoclonal Anti-CD41/CD61 antibody produced in mouse, clone PAC-1,
Espèces réactives
human
Application
flow cytometry
Anticorps anti-intégrine β3, clone B3A, sans azoture, clone B3A, Chemicon®, from mouse,
Espèces réactives
human
Application
flow cytometry
western blot
Anticorps anti-intégrine bêta-3, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, canine, chimpanzee, human, pig, porcine, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Integrin β3 Antibody, clone 25E11, clone 25E11, Chemicon®, from mouse,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

immunoprecipitation (IP)

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Tirofiban hydrochloride monohydrate, ≥98% (HPLC),
Espèce(s)
human
Tirofiban, ≥98.5% (HPLC),
Espèce(s)
human
Acetylsalicylic acid, ≥99.0%,
Espèce(s)
human

Small Molecule - Mixed Agonist/Antagonist

Référence du produit
Description
Espèce(s)
Arg-Gly-Asp-Ser, ≥95% (HPLC),
Espèce(s)
mouse, human
Acetylsalicylic acid, ≥99.0%,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Itgb3,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ITGB3, RP11-290H9.2,
Espèce(s)
human