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IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Synonymes:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-IMPDH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Ribavirin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Ribavirin, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Ribavirin impurity standard, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
Ribavirin, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Ribavirin, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IMPDH1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Impdh1,
Espèce(s)
mouse