HTR3A
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
Synonymes:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Espèce(s):
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), chicken HTR3A (428247), cow HTR3A (617674), Horse HTR3A (100009690), domestic cat HTR3A (101098004), dog HTR3A (489399), domestic guinea pig Htr3a (100135547), naked mole-rat Htr3a (101714088) ...Plus
ID UniProtKB:
ID du gène:
- Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
- Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
- Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
- naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
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Small Molecule - Agonist
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Description
Espèce(s)
Small Molecule - Allosteric Modulator
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Small Molecule - Antagonist
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Espèce(s)
Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Antibodies
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Espèces réactives
Application
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Small Molecule - Inhibitor
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Small Molecule - Ligand
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Small Molecule - Metabolite
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Small Molecule - Precursor
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