HRH1
histamine receptor H1
Synonymes:
H1-R, hisH1
Espèce(s):
Human HRH1 (3269), Mouse Hrh1 (15465), Rat Hrh1 (24448), Zebrafish hrh1 (735302), dog HRH1 (403813), domestic cat HRH1 (101088314), cow HRH1 (281231), Horse HRH1 (100034110), chicken HRH1 (100858928), domestic guinea pig Hrh1 (100135539) ...Plus
ID UniProtKB:
ID du gène:
- Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(15465) histamine receptor H1
- Rat(24448) histamine receptor H 1
- Zebrafish(735302) histamine receptor H1
- dog(403813) histamine receptor H1
- domestic cat(101088314) histamine receptor H1
- cow(281231) histamine receptor H1
- Horse(100034110) histamine receptor H1
- chicken(100858928) histamine receptor H1
- domestic guinea pig(100135539) histamine receptor H1
- domestic guinea pig(100730517) histamine receptor H1
- naked mole-rat(101715481) histamine receptor H1
- sheep(101121717) histamine receptor H1
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Histamine dihydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Chlorpheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Espèces réactives
bovine, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Référence du produit
Description
Espèce(s)
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Small Molecule - Ligand
Small Molecule - Metabolite
Référence du produit
Description
Espèce(s)