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Merck

GPX4

glutathione peroxidase 4

Synonymes:
GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2879) Summary: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
  • Mouse(625249) glutathione peroxidase 4
  • Rat(29328) glutathione peroxidase 4
  • Thale Cress(819427) glutathione peroxidase 4
  • domestic cat(101095956) glutathione peroxidase 4
  • chicken(374056) glutathione peroxidase 4
  • cow(286809) glutathione peroxidase 4
  • domestic guinea pig(100730119) glutathione peroxidase 4
  • naked mole-rat(101708875) glutathione peroxidase 4
  • Goat(100860867) glutathione peroxidase 4
  • sheep(101113149) glutathione peroxidase 4

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GPX4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-Glutathione Peroxidase 4 Antibody, clone Mab63-1, clone Mab63-1, from mouse, purified by affinity chromatography,
Espèces réactives
human, mouse
Application
dot blot
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-GPx4 Antibody, clone 1B4, clone 1B4, from rat,
Espèces réactives
mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-GPX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-GPX4, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GPX4,
Espèce(s)
human