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Merck

GPX1

glutathione peroxidase 1

Synonymes:
GPXD, GSHPX1
Espèce(s):
Human GPX1 (2876), Mouse Gpx1 (14775), Rat Gpx1 (24404), Thale Cress GPX1 (817046), chicken GPX1 (100857115), domestic cat GPX1 (101083751), cow GPX1 (281209), Horse GPX1 (100053396), dog GPX1 (442961), sheep GPX1 (100820742) ...Plus
ID UniProtKB:
P07203, E9PAS1, Q7Z5H1, Q9BW12
ID du gène:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
A8592
Anticorps monoclonal ANTI-FLAG® M2-peroxydase (HRP) antibody produced in mouse, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
all
Application
ELISA
SAB2700534
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
alligator, human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB2500468
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, pig
Application
ELISA
immunohistochemistry
western blot
SAB1302824
ANTI-GPX1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
western blot
SAB5700925
Anti-GPX1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP8010
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU218531
MISSION® esiRNA, targeting human GPX1,
Espèce(s)
human