Accéder au contenu
Merck

GHR

growth hormone receptor

Synonymes:
GHBP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2690) Summary: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(14600) growth hormone receptor
  • Rat(25235) growth hormone receptor
  • chicken(408184) growth hormone receptor
  • cow(280805) growth hormone receptor
  • domestic cat(101093244) growth hormone receptor
  • dog(403721) growth hormone receptor
  • naked mole-rat(101716037) growth hormone receptor
  • domestic guinea pig(100135527) growth hormone receptor
  • Goat(100860790) growth hormone receptor
  • Domestic Rabbit(100009325) growth hormone receptor
  • sheep(443333) growth hormone receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Référence du produit
Description
Espèce(s)
Human GHR ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Growth Hormone Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
mouse
Application
immunohistochemistry
western blot
Anti-GHR antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-GHR Mouse mAb (3A12), liquid, clone 3A12, Calbiochem®,
Espèces réactives
human
Application

Small Molecule - Ligand

Référence du produit
Description
Espèce(s)
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
GHBP human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
Espèce(s)
human
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GHR,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ghr,
Espèce(s)
mouse