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Merck

FOXP2

forkhead box P2

Synonymes:
CAGH44, SPCH1, TNRC10
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(93986) Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(114142) forkhead box P2
  • Rat(500037) forkhead box P2
  • Zebrafish(555242) forkhead box P2
  • chicken(769935) forkhead box P2
  • dog(482413) forkhead box P2
  • domestic cat(100134847) forkhead box P2
  • Goat(100860795) forkhead box P2
  • Domestic Rabbit(100328793) forkhead box P2
  • sheep(101110051) forkhead box P2
  • naked mole-rat(101699542) forkhead box P2
  • domestic guinea pig(100717297) forkhead box P2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-FoxP2 Antibody, clone FOXP2-73A/8, clone FOXP2-73A/8, from mouse,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-FOXP2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5312, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
Anti-FOXP2 antibody produced in rabbit, AB1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-FOXP2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5310, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry
Anti-FOXP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human FOXP2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Foxp2,
Espèce(s)
mouse