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Merck

CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

Synonymes:
CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1562) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • sheep(100568290) cytochrome P450 2C18
  • chicken(414841) cytochrome P450, family 2, subfamily C, polypeptide 18
  • cow(535243) cytochrome P450, family 2, subfamily C, polypeptide 18
  • dog(415122) cytochrome P450 2C21

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CYP2C18 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-Cyp2C18 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Sulfaphenazole, ≥98%,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CYP2C18,
Espèce(s)
human