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Merck

CRHR1

corticotropin releasing hormone receptor 1

Synonymes:
CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRHR1f
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1394) Summary: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346. [provided by RefSeq, Jan 2012]
  • Mouse(12921) corticotropin releasing hormone receptor 1
  • Rat(58959) corticotropin releasing hormone receptor 1
  • sheep(443025) corticotropin releasing hormone receptor 1
  • Domestic Rabbit(100302436) corticotropin releasing hormone receptor 1
  • domestic guinea pig(100729987) corticotropin releasing hormone receptor 1
  • naked mole-rat(101721828) corticotropin releasing hormone receptor 1
  • Zebrafish(567940) corticotropin releasing hormone receptor 1
  • cow(281716) corticotropin releasing hormone receptor 1
  • Horse(100065598) corticotropin releasing hormone receptor 1
  • chicken(374218) corticotropin releasing hormone receptor 1
  • dog(610380) corticotropin releasing hormone receptor 1
  • domestic cat(723971) corticotropin releasing hormone receptor 1
  • domestic cat(101089308) corticotropin releasing hormone receptor 1

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
NBI 27914, ≥98% (HPLC),
Espèce(s)
human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Espèce(s)
human, rat, mouse

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CRHR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
ANTI-CRFR1 (Q103) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
western blot
Anti-CRFR1/CRHR1 Antibody, clone 1N21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

western blot
Anti-CRHR1/CRF-R (AA 107-117) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-Corticotropin-Releasing Factor Receptor 1 Antibody, Chemicon®, from rabbit,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CRHR1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Crhr1,
Espèce(s)
mouse