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Merck

ADRB2

adrenoceptor beta 2, surface

Synonymes:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
(−)-Isoproterenol hydrochloride, ,
Espèce(s)
human
Clenbuterol hydrochloride, ≥95%,
Espèce(s)
human
Salbutamol, ,
Espèce(s)
human
Formoterol fumarate dihydrate, >98% (HPLC),
Espèce(s)
human
Fenoterol hydrobromide, ,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Espèce(s)
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Propranolol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Propranolol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-β-2 Adrenergic Receptor antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Adrb2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ADRB2,
Espèce(s)
human