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Merck

ACVR2A

activin A receptor, type IIA

Synonymes:
ACTRII, ACVR2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(92) Summary: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
  • Mouse(11480) activin receptor IIA
  • Rat(29263) activin A receptor, type IIA
  • chicken(396324) activin A receptor, type IIA
  • dog(476140) activin A receptor, type IIA
  • domestic cat(101097750) activin A receptor, type IIA
  • Horse(100049823) activin A receptor, type IIA
  • cow(281598) activin A receptor, type IIA
  • sheep(443304) activin A receptor, type IIA
  • domestic guinea pig(100731791) activin A receptor, type IIA
  • naked mole-rat(101707586) activin A receptor, type IIA

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ELISA

Référence du produit
Description
Espèce(s)
Human Activin R2A ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ACVR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Acvr2a,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ACVR2A,
Espèce(s)
human