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Solid Phase Extraction (SPE)

The Visiprep™ SPE Vacuum Manifold has a valve system for precise flow rate control and more reproducible extractions.

Solid phase extraction (SPE) is a technique designed for rapid, selective sample preparation and purification prior to the chromatographic analysis (e.g. HPLC, GC, TLC). In SPE, one or more analytes from a liquid sample are isolated by extracting, partitioning, and/or adsorbing onto a solid stationary phase.

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Solid Phase Extraction (SPE) and QuEChERS
Solid Phase Extraction (SPE) and QuEChERS

Discover diverse materials for solid phase extraction (SPE) and QuEChERS sample prep. Cartridges, tubes, plates, and more available.

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Various HPLC and UHPLC products
HPLC Columns

Achieve precise separations with our extensive HPLC column collection. Enhance retention, resolution, and selectivity. Order today.
 

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GC Columns, Accessories & Adsorbents
GC Columns, Accessories & Adsorbents

Achieve superior GC performance with our columns, consumables, and accessories. Explore Supelco® offerings.

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Featured Articles
Determination of Formaldehyde and Acetaldehyde in Air Using DNPH Cartridges and Automated On-Line Desorption Followed by HPLC
Carbonyl compounds react within the DNPH cartridge to form immobilized hydrazones, which can be subjected to automated desorption and HPLC analysis with UV detection.
The Effect of Container Materials on Production of Light Induced Off-Flavors in Milk – A Study Using SPME-GC-MS
Various plastics used as barriers to the production of off-flavors in light exposed milk were examined using HS-SPME with a new Carboxen®/PDMS coated Nitinol fiber followed by GC-MS analysis allowing detection of low MW analytes at levels <1 ng/mL.
Analysis of Pesticide Residues in Ginger Powder Using QuEChERS Extraction and Clean-up with a Novel Dual Layer SPE Cartridge
The odor and pungency of ginger is due to the presence of terpenes, gingerols and shogaols. These compounds contribute to the highly complex matrix of ginger, which subsequently presents a challenge in low level analyses of contaminants. A novel 2-layer SPE cartridge efficiently reduces background for pesticide determination.
HybridSPE-Phospholipid Technology
This Sigma-Aldrich article discusses how the HybridSPE-Phospholipid Technology works and how the phospholipids are removed.
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