Single-Use Mixers

Mobius^® single-use mixing solutions deliver efficient mixing of pharmaceutical ingredients from intermediate to final drug products, as well as preparation of process solutions such as buffers and media. Unlike traditional stainless steel mixers, single-use mixers reduce downtime spent on process steps such as cleaning in place (CIP), sterilization in place (SIP), cleaning validation, and process engineering. Mobius^® single-use mixing solutions are capable of speeds up to 1000 RPM, meeting the broadest range of mixing production requirements. Mobius^® flexibility offers you a choice of just the right filter, connector, and tubing options for your specific application and environment, including sterile interfaces, from fermentation to final fill. 

Mobius^® single-use mixing solutions include a complete range of mixers in sizes from 10 L to 3,000 L. Both Mobius® MIX and Mobius^® Power MIX product lines offer proven operational efficiency, saving valuable processing and validation time. Our scalable, ready-to-use systems and processing technologies reduce the risk of contamination and deliver reproducible results. 

• Easy setup and use
• Closed, zero dead-leg sterile sampling system enables representative samples
• Single-use technology for increased production capacity in multiproduct facilities
• Validation, quality, and regulatory compliance support

Mobius^® MIX: the mixing solution of choice for gentle mixing applications such as protein and shear-sensitive product homogenization

The Mobius^® MIX family of single-use mixers is offered in sizes from 10 L to 1,000 L. Each single-use mixing container includes our proprietary, magnetically driven levitating impeller for improved mixing consistency and efficiency.

• Available in 10 L, 50 L, 100 L, 200 L, 500 L, and 1,000 L sizes
• Fast, easy setup and use
• Compact footprint and mobile carrier construction for enhanced flexibility
• Instant-on electronics with no warmup needed

Mobius^® Power MIX: the mixing solution of choice for hard-to-dissolve materials and buffer preparation

The Mobius^® Power MIX family of single-use mixers combines high-performance mixing technology with design features that make it easy to use. The impeller design and motor are based on our magnetically coupled NovAseptic^® mixing technology, a proven mixing technology used with stainless steel tanks for efficient mixing of the most challenging buffer, media, and biopharmaceutical ingredients.

• Available in a wide range of sizes and materials
  • 100 L, 200 L, 500 L (HDPE and jacketed stainless steel)
  • 1,000 L, 2,000 L, 2,500 L, and 3,000 L (jacketed stainless steel only)
• Stainless steel versions have wide doors that open to one half the mixer's diameter for easy bag loading
• Options on the stainless steel versions include integrated load cells and temperature sensor

Mobius^® mixers can be monitored and controlled locally or remotely. Plug the ready to connect control box to the network and use Ethernet IP communication protocol to monitor speed, weight, temperature, pH and conductivity remotely. The ready to connect control box is a separate box on a four wheels chassis that can be easily moved around the Mobius^® mixer carrier. Optimize your layout and get a better access to control your Mobius^® mixing system by freely positioning the control box around it. The 21 CFR Part 11 compliant data recorder option displays data trends in real time and ensures process data integrity when recording.

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Product Selection

Application Note: Comparison Between Experimental Data and Computational Fluid Dynamics in Mixing Applications
Datasheet: Mobius^® Power MIX Single-use Mixing System
Datasheet: Mobius^® Power MIX 2000
Datasheet: Mobius^® Single-use Mixing Solution
Datasheet: PureFlex™ Single-use Process Container Films
Technical Brief: Holistic Buffer Preparation

Product Operations

Application Note: Mobius^® Power MIX: Scalability in Mixing
Application Note: Mobius^® Power MIX 100
Application Note: Mobius^® Power MIX 200
Application Note: Mobius^® Power MIX 500
Technical Brief: Mobius^® MIX500 Disposable Mixing System Characterization
Application Note: Mobius^® Power MIX 1000
Application Note: Mobius^® Power MIX 2000
Application Note: Mobius^® MIX 200 Disposable Mixing System
Application Note: 1X PBS (Phosphate Buffered Saline) Buffer Mixing Optimization
Application Note: Vent Filter Sizing for Mobius^® Single-use Mixing Solution
Technical Brief: Mobius^® MIX 100 Disposable Mixing System Characterization
Application Note: Cell Culture Media Microfiltration and Mixing: Reducing Risk with Single-use Technology
Application Note: Compatibility of a Mobius^® Single-use Solution for ADC Processing
EMPROVE^® Material Qualification Dossier for Mobius^® Single-use Mixing Systems