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Sulfamonomethoxine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide, 4-Methoxy-6-sulfanilamidopyrimidine, N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide, SMM

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
Molecular Weight:
280.30
Beilstein:
621128
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤3.0% water

application(s)

clinical testing

format

neat

SMILES string

COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1

InChI

1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

WMPXPUYPYQKQCX-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide
Sulfamonomethoxine is classified under the sulfonamide group of compounds.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamonomethoxine may be used as an analytical reference standard for the determination of sulfamonomethoxine in:
  • Tissues, milk and eggs of food-producing animals by ultrasound-assisted extraction (UAE) and liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
  • Food samples of animal origin by QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction procedure, SOSLE (salting-out supported liquid extraction) method and nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
  • Bovine muscles by hydrophilic interaction liquid chromatography (HILIC) combined with LC-MS/MS.
  • Commercial eggs by liquid-liquid extraction (LLE), hybrid solid-phase extraction (SPE) and LC-MS/MS.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Analysis of trace levels of sulfonamides in fish tissue using micro-scale pipette tip-matrix solid-phase dispersion and fast liquid chromatography tandem mass spectrometry.
Shen Q, et al.
Food Chemistry, 194, 508-515 (2016)
Caixia Jin et al.
Ecotoxicology (London, England), 18(7), 878-885 (2009-06-26)
Investigation of the toxic effects of three veterinary drugs [sulfadiazine sodium (SDS), sulfamonomethoxine sodium (SMMS), and enrofloxacin (EFLX)] on seed germination, root elongation and shoot elongation of wheat (Triticum aestivum L.), Chinese cabbage (Brassica campestris L.) and tomato (Cyphomandra betacea)
Jingchun Yan et al.
Chemosphere, 87(2), 111-117 (2011-12-24)
Ferrous hydroxide colloids were prepared and characterized as an activator of H(2)O(2) for decomposing organic pollutants, such as Rhodamine B, sulfamonomethoxine (SMM) and 4-nitrophenol (4-NP). As major reactive oxygen species, hydroxyl radicals were confirmed to be generated in the activation
Multiresidue method for the simultaneous determination of veterinary medicinal products, feed additives and illegal dyes in eggs using liquid chromatography-tandem mass spectrometry.
Piatkowska M, et al.
Food Chemistry, 197, 571-580 (2016)
G Zhang et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(4), 413-423 (2008-03-19)
A rapid lateral flow immunoassay screening method has been developed for the determination of sulfamonomethoxine (SMM) residues in swine urine. For this purpose, a specific monoclonal antibody (mAb), SMM4B9 for SMM, was generated and characterized. The mAb showed low cross-reactivity

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