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Merck

RIPK3

receptor-interacting serine-threonine kinase 3

Synonyms:
RIP3
Species:
UniProtKB ID:
Gene ID:
  • Human(11035) Summary: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(56532) receptor-interacting serine-threonine kinase 3
  • Rat(246240) receptor-interacting serine-threonine kinase 3
  • cow(507427) receptor-interacting serine-threonine kinase 3
  • sheep(101118877) receptor-interacting serine-threonine kinase 3
  • domestic guinea pig(100734737) receptor-interacting serine-threonine kinase 3
  • naked mole-rat(101719112) receptor-interacting serine-threonine kinase 3
  • dog(608486) receptor-interacting serine-threonine kinase 3
  • domestic cat(101097985) receptor-interacting serine-threonine kinase 3

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RIP3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-RIPK3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-RIPK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-RIP3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-RIPK3/RIP3 Antibody, clone 8G7, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
RIPK3, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ripk3,
Species
mouse
MISSION® esiRNA, targeting human RIPK3,
Species
human