NOS1
nitric oxide synthase 1 (neuronal)
Synonyms:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
Species:
Human NOS1 (4842), Mouse Nos1 (18125), Rat Nos1 (24598), Zebrafish nos1 (60658), domestic cat NOS1 (101100342), cow NOS1 (536132), Horse NOS1 (100051079), dog NOS1 (477498), chicken NOS1 (427721), naked mole-rat Nos1 (101711993) ...More
UniProtKB ID:
Gene ID:
- Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
- Mouse(18125) nitric oxide synthase 1, neuronal
- Rat(24598) nitric oxide synthase 1, neuronal
- Zebrafish(60658) nitric oxide synthase 1 (neuronal)
- domestic cat(101100342) nitric oxide synthase 1 (neuronal)
- cow(536132) nitric oxide synthase 1 (neuronal)
- Horse(100051079) nitric oxide synthase 1 (neuronal)
- dog(477498) nitric oxide synthase 1 (neuronal)
- chicken(427721) nitric oxide synthase 1 (neuronal)
- naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
- Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
- domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NOS1 (Ab-852) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Anti-NNOS antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-n-NOS (pSer852) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-n-NOS (pSer852) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Nitrotyrosine Antibody, clone 1A6, clone 1A6, Upstate®, from mouse,
Species Reactivity
vertebrates
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Kits
Product Number
Description
Species
Nitric Oxide Synthase Detection System, Fluorimetric, sufficient for 200 reactions,
Species
human
Small Molecule - Precursor
Product Number
Description
Species
L-Arginine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Species
rat, human
esiRNA
Product Number
Description
Species