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Merck

KRAS

Kirsten rat sarcoma viral oncogene homolog

Synonyms:
C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Species:
UniProtKB ID:
Gene ID:
  • Human(3845) Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
  • Mouse(16653) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • Rat(24525) Kirsten rat sarcoma viral oncogene
  • Zebrafish(445289) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • cow(541140) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • dog(403871) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • chicken(418207) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • sheep(101114005) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • domestic guinea pig(100716262) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • naked mole-rat(101718997) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Kras Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-KRAS antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-K-Ras4A Antibody, Isoform-specific, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot
Anti-Pan-Ras Antibody, clone RAS 10, clone RAS 10, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot

Proteins

Product Number
Description
Species
KRAS (Mature Form), Active, PRECISIO® Kinase, recombinant,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse KRAS,
Species
mouse
MISSION® esiRNA, targeting human KRAS,
Species
human