ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
Species:
Human ITGA2B (3674), Mouse Itga2b (16399), Rat Itga2b (685269), Zebrafish itga2b (445380), dog ITGA2B (403789), domestic cat ITGA2B (101100930), cow ITGA2B (515011), Horse ITGA2B (100009697), sheep ITGA2B (101115719), domestic guinea pig Itga2b (100727374)
UniProtKB ID:
Gene ID:
- Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
- Mouse(16399) integrin alpha 2b
- Rat(685269) integrin, alpha 2B
- Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD41/ITGA2B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Integrin αIIb Antibody, cytoplasmic domain, serum, Chemicon®,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
Monoclonal Anti-CD41 antibody produced in rat, clone MWReg30,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-CD41-FITC antibody produced in mouse, clone MEM-06, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD41-APC antibody produced in mouse, clone MEM-06, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Small Molecule - Inhibitor
Product Number
Description
Species