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Merck

HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

Synonyms:
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
Species:
UniProtKB ID:
Gene ID:
  • Human(3028) Summary: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(15108) hydroxysteroid (17-beta) dehydrogenase 10
  • Rat(63864) hydroxysteroid (17-beta) dehydrogenase 10
  • Zebrafish(450078) hydroxysteroid (17-beta) dehydrogenase 10
  • chicken(425758) hydroxysteroid (17-beta) dehydrogenase 10
  • cow(281809) hydroxysteroid (17-beta) dehydrogenase 10
  • domestic cat(101090672) hydroxysteroid (17-beta) dehydrogenase 10
  • dog(480930) hydroxysteroid (17-beta) dehydrogenase 10
  • domestic guinea pig(100718814) hydroxysteroid (17-beta) dehydrogenase 10
  • naked mole-rat(101712281) hydroxysteroid (17-beta) dehydrogenase 10
  • sheep(101119880) hydroxysteroid (17-beta) dehydrogenase 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ERAB/HSD17B10 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-HSD17B10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-HSD17B10 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-HSD17B10 Antibody, clone 5F3, clone 5F3, from mouse,
Species Reactivity
human, mouse
Application
electron microscopy
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
HSD17B10, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HSD17B10,
Species
human
MISSION® esiRNA, targeting mouse Hsd17b10,
Species
mouse