CD160
CD160 molecule
Synonyms:
BY55, NK1, NK28
Species:
Human CD160 (11126), Mouse Cd160 (54215), Rat Cd160 (502585), domestic guinea pig Cd160 (101788999), dog CD160 (483158), domestic cat CD160 (100125861)
UniProtKB ID:
Gene ID:
- Human(11126) Summary: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]
- Mouse(54215) CD160 antigen
- Rat(502585) CD160 molecule
- domestic guinea pig(101788999) CD160 molecule
- dog(483158) CD160 molecule
- domestic cat(100125861) CD160 molecule
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD160 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CD160-APC antibody produced in mouse, clone BY55,
Species Reactivity
Application
flow cytometry
Monoclonal Anti-CD160 antibody produced in mouse, clone BY55,
Species Reactivity
human
Application
flow cytometry
Proteins
Product Number
Description
Species