ALOX5AP
arachidonate 5-lipoxygenase-activating protein
Synonyms:
FLAP
Species:
Human ALOX5AP (241), Mouse Alox5ap (11690), Rat Alox5ap (29624), naked mole-rat Alox5ap (101704126), domestic guinea pig Alox5ap (100733727), Zebrafish alox5ap (337376), domestic cat ALOX5AP (101090316), cow ALOX5AP (613869), Horse ALOX5AP (100034178), dog ALOX5AP (477323)
UniProtKB ID:
Gene ID:
- Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
- Mouse(11690) arachidonate 5-lipoxygenase activating protein
- Rat(29624) arachidonate 5-lipoxygenase activating protein
- naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
- domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
- Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein
- domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
- cow(613869) arachidonate 5-lipoxygenase-activating protein
- Horse(100034178) arachidonate 5-lipoxygenase-activating protein
- dog(477323) arachidonate 5-lipoxygenase-activating protein
- chicken(770904) arachidonate 5-lipoxygenase-activating protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ALOX5AP (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ALOX5AP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-FLAP/ALOX5AP, C-Terminal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-FLAP/ALOX5AP (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species