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LC/MS Analysis of Drugs of Abuse on Ascentis® Express RP-Amide

LC/MS Analysis of Drugs of Abuse on Ascentis® Express RP-Amide application for HPLC

Materialien

Analytische Säule

Produkt-Nr.
Beschreibung
Preisangaben

Ascentis® Express RP-Amid, 2,7 μm HPLC-Säule

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

Komponente der mobilen Phase

Produkt-Nr.
Beschreibung
Preisangaben

Ammoniumformat

eluent additive for LC-MS, LiChropur, ≥99.0%

Standard

Produkt-Nr.
Beschreibung
Preisangaben

Benzoylecgonin -Lösung

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Cocaethylen -Lösung

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

EDDP perchlorate

ampule of 10 mg, certified reference material, Cerilliant®

(±)-Methadon -Lösung

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

CONDITIONS

column

Ascentis Express RP Amide, 10 cm x 2.1 mm I.D., 2.7 μm particles (53913-U)

mobile phase

[A] 10 mM ammonium formate in water; [B] 10mM ammonium formate in acetonitrile; (75:25, A:B)

flow rate

0.2 mL/min

column temp.

35 °C

detector

ESI(+)

injection

2 μL

sample

500 ng/mL in water

Beschreibung

Hinweis zur Analyse

This applic.ation demonstrates the suitability of Ascentis Express RP-Amide for the efficient separation of common drink additives used in diet cola

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany