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  • Convenient method for the preparation of Weinreb amides via Pd-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure.

Convenient method for the preparation of Weinreb amides via Pd-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure.

Organic letters (2006-10-06)
Joseph R Martinelli, Dominique M M Freckmann, Stephen L Buchwald
ZUSAMMENFASSUNG

[reaction: see text] The direct transformation of aryl bromides into the corresponding Weinreb amides via Pd-catalyzed aminocarbonylation at atmospheric pressure is reported.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
4,5-Bis-(diphenylphosphino)-9,9-dimethylxanthen, 97%