Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical

Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical

Clinica chimica acta; international journal of clinical chemistry (2017-01-17)

M Mirzaian, P Wisse, M J Ferraz, A R A Marques, P Gaspar, S V Oussoren, K Kytidou, J D C Codée, G van der Marel, H S Overkleeft, J M Aerts

PMID28089753

ZUSAMMENFASSUNG

Free sphingoid bases (lysosphingolipids) of primary storage sphingolipids are increased in tissues and plasma of several sphingolipidoses. As shown earlier by us, sphingoid bases can be accurately quantified using UPLC-ESI-MS/MS, particularly in combination with identical