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Merck

Antimicrobial metallopeptides with broad nuclease and ribonuclease activity.

Chemical communications (Cambridge, England) (2013-02-06)
Jeff C Joyner, W F Hodnick, Ada S Cowan, Deepika Tamuly, Rachel Boyd, J A Cowan
ZUSAMMENFASSUNG

Metallopeptides containing both the complex Cu(2+)-glycyl-glycyl-histidine (Cu-GGH) and the sequence WRWYCR were shown to possess antimicrobial activity against a variety of pathogenic bacteria, as well as bind to and cleave a variety of nucleic acids, suggesting potential mechanisms for antimicrobial activity that involve binding and/or irreversible cleavage of bacterial nucleic acids.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Gly-Gly-His