- Reactions of difluorocarbene with organozinc reagents.
Reactions of difluorocarbene with organozinc reagents.
Organic letters (2013-02-02)
Vitalij V Levin, Artem A Zemtsov, Marina I Struchkova, Alexander D Dilman
PMID23368906
ZUSAMMENFASSUNG
Reactions of difluorocarbene with benzyl and alkylzinc halides leading to fluorinated organozinc species have been described. The generated α-difluorinated organozinc reagents are reasonably stable in solution and can be quenched with external electrophiles (iodine, bromine, proton), affording compounds containing the CF(2) fragment.