Direkt zum Inhalt
Merck
  • The development of a facile tandem Wolff/Cope rearrangement for the synthesis of fused carbocyclic skeletons.

The development of a facile tandem Wolff/Cope rearrangement for the synthesis of fused carbocyclic skeletons.

Journal of the American Chemical Society (2003-11-06)
Richmond Sarpong, Julius T Su, Brian M Stoltz
ZUSAMMENFASSUNG

A set of mild processes for the conversion of vinyl cyclopropyl diazo ketones to highly functionalized cycloheptadienones and vinyl cyclopentenones by use of a target-inspired tandem Wolff/Cope rearrangement sequence is described. A divergent reaction course of the vinyl cyclopropyl diazo ketone substrates under sono- or photochemical activation provides good to excellent yields (55-98%) of the product cycloheptadienones and vinyl cyclopentenones.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Cycloheptanon, 99%
SKU
Packungsgröße
Verfügbarkeit
Preis
Menge