Direkt zum Inhalt
Merck

Click-Crosslinked Injectable Gelatin Hydrogels.

Advanced healthcare materials (2016-01-26)
Sandeep T Koshy, Rajiv M Desai, Pascal Joly, Jianyu Li, Rishi K Bagrodia, Sarah A Lewin, Neel S Joshi, David J Mooney
ZUSAMMENFASSUNG

Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells, establishment of 3D elongated cell morphologies, and biodegradation when injected in vivo.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Alkyne functionalized gelatin, degree of substitution > 80%