V900422

Folsäure

Vetec^™, reagent grade, ≥97%

• Synonym(e): PteGlu, Pteroyl-L-glutaminsäure, Vitamin M
• Empirische Formel (Hill-System): C₁₉H₁₉N₇O₆
• CAS-Nummer: 59-30-3
• Molekulargewicht: 441.40
• Beilstein: 100781
• EG-Nummer: 200-419-0
• MDL-Nummer: MFCD00079305
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329829830

Eigenschaften

• Qualität: reagent grade
• Produktlinie: Vetec^™
• Assay: ≥97%
• Form: powder
• Methode(n): HPLC: suitable
• Farbe: yellow to orange
• mp (Schmelzpunkt): >285 °C
• SMILES String: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChIKey: OVBPIULPVIDEAO-LBPRGKRZSA-N

Beschreibung

Allgemeine Beschreibung

Folic acid belongs to vitamin B group and is also called as vitamin B₉ or folate. It is present as 5-methyltetrahydrofolate in humans. Grains, fruits and vegetables are dietary sources of folate. Pteroylmonoglutamate is a synthetic folate which comprises single glutamate and exists in the oxidized state.

Biochem./physiol. Wirkung

Folic acid is essential for cell growth, brain functioning and plays a key role on serine production from glycine. It also coordinates with vitamin B₁₂ in maintaining iron levels. Deficiency of folate is implicated in megaloblastic anemia. Folic acid aids in the repair and synthesis of DNA. Dietary supplementation and fortification of folate in foods is recommended for pregnant women especially in the first trimester to avoid congenital malformation and neural tube defects (NTDs). However, folate fortification may also impose a moderate risk of developing prostate cancer. Supplementation of folate to colon cancer cells diminishes iron levels and impairs the cell division.

Rechtliche Hinweise

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1