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Merck

SAB4500345

Sigma-Aldrich

Anti-CNR1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

CANN6, CB-R, CB1, CNR1, Cannabinoid receptor 1

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 52 kDa

Speziesreaktivität

mouse, rat, human

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CNR1(1268)

Allgemeine Beschreibung

Anti-CNR1 Antibody detects endogenous levels of total CNR1 protein.
CNR1 (cannabinoid receptor 1) is a member of the class A G protein-coupled receptor (GPCR) family. It is also known as the type-1 cannabinoid receptor (CB1). It is expressed at high level in the brain and the central nervous system. It is located on human chromosome 6q15.

Immunogen

The antiserum was produced against synthesized peptide derived from human CNR1.

Immunogen Range: 151-200

Biochem./physiol. Wirkung

CNR1 (cannabinoid receptor 1) participates in most of the activities of the brain and body. It is sensitive to hebephrenic schizophrenia. Experimental studies hypothesize that aberrations in CNR1 gene increases the risk of susceptibility to substance abuse.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia.
Ujike H, et al.
Molecular Psychiatry, 7(5), 515-515 (2002)
Cannabinoid receptor gene (CNR1): association with iv drug use.
Comings DE, et al.
Molecular Psychiatry, 2(2), 161-161 (1997)
The incentive salience of alcohol: translating the effects of genetic variant in CNR1.
Hutchison KE, et al.
Archives of General Psychiatry, 65(7), 841-850 (2008)
The CB1 receptor as the cornerstone of exostasis.
Piazza PV, et al.
Neuron, 93(6), 1252-1274 (2017)
Crystal structure of the human cannabinoid receptor CB 1.
Hua T, et al.
Cell, 167(3), 750-762 (2016)

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