Direkt zum Inhalt
Merck

SAB1405562

Sigma-Aldrich

Anti-CAT antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(e):

MGC138422, MGC138424

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen ~59.8 kDa

Speziesreaktivität

human

Methode(n)

indirect immunofluorescence: suitable
western blot: 1 μg/mL

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CAT(847)

Allgemeine Beschreibung

Catalase (CAT) is an antioxidant enzyme. CAT gene is located on human chromosome 11p13. CAT is present in peroxisomes of most aerobic organisms. It is a heme enzyme expressed mainly in liver.

Immunogen

CAT (NP_001743.1, 1 a.a. ~ 527 a.a) full-length human protein.

Sequence
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL

Biochem./physiol. Wirkung

Catalase (CAT) protects different cell types from the harmful effects of hydrogen peroxide. It is involved in idiopathic male infertility. CAT converts hydrogen peroxide to water and molecular oxygen. CAT promotes resistance against many diseases. Mutations in CAT is linked to acatalasemia.

Physikalische Form

Solution in phosphate buffered saline, pH 7.4

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Produkt-Auswahlhilfe.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

A new type 1 diabetes susceptibility locus containing the catalase gene (chromosome 11p13) in a Russian population
Chistiakov D, et al.
Diabetes/metabolism Research and Reviews, 20(3) (2004)
Regulation of catalase expression in healthy and cancerous cells
Glorieux C, et al.
Free Radical Biology & Medicine, 87(3) (2015)
A novel catalase mutation (a GA insertion) causes the Hungarian type of acatalasemia
Goth L , et al.
Blood Cells, Molecules and Diseases, 26(2) (2000)
The role of catalase C262T gene polymorphism in the susceptibility and survival of cancers
Wang C, et al.
Scientific Reports, 6(5), 26973-26973 (2016)
Structure and heme environment of beef liver catalase at 2.5 A resolution
Reid T, et al.
Proceedings of the National Academy of Sciences of the USA, 78(8) (1981)

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.