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N4377

Sigma-Aldrich

4-Nitrophenyl valerate

chromogenic, ≥98% (TLC), liquid

Synonym(e):

Pentanoic acid 4-nitrophenyl ester

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About This Item

Empirische Formel (Hill-System):
C11H13NO4
CAS-Nummer:
1956-07-6
Molekulargewicht:
223.23
MDL-Nummer:
MFCD00057614
UNSPSC-Code:
12352204
PubChem Substanz-ID:
24897702
NACRES:
NA.83

product name

4-Nitrophenyl valerate, liquid

Assay

≥98% (TLC)

Form

liquid

Farbe

faintly yellow to dark yellow

Lagertemp.

−20°C

SMILES String

CCCCC(=O)Oc1ccc(cc1)N(=O)=O

InChI

1S/C11H13NO4/c1-2-3-4-11(13)16-10-7-5-9(6-8-10)12(14)15/h5-8H,2-4H2,1H3

InChIKey

RJQXEHRFVKJLJO-UHFFFAOYSA-N

Anwendung

4-Nitrophenyl valerate has been used as a substrate solution to measure the rate of p-nitrophenol formation using p-nitrophenyl valerate as substrate. It has also been used as a substrate to measure general esterase activity in hepatopancreas extracts.

Biochem./physiol. Wirkung

4-Nitrophenyl valerate acts as a model substrate for carboxylesterase and butyrylcholinesterase.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Xia Wen et al.
Toxicology, 416, 15-22 (2019-01-28)
Hepatic carboxylesterases (Ces) catalyze the metabolism of drugs, environmental toxicants, and endogenous lipids and are known to be regulated by multiple nuclear receptors. Perfluorooctanoic acid (PFOA) is a synthetic fluorochemical that has been associated with dyslipidemia in exposed populations. In
Sonja Kübelbeck et al.
Macromolecular bioscience, 18(7), e1800095-e1800095 (2018-06-06)
Herein, the synthesis of enzyme-polymer conjugates is reported. Four different activated polymers (mPEG-aldehyde, mPEG-NHS, maltodextrin-aldehyde, carboxymethyl cellulose aldehyde) are conjugated to the surface of protease, α-amylase, and lipase using two different strategies (reductive amination and alkylation with NHS-activated acid). Although
Mikael Skaanning Jørgensen et al.
Microbial cell factories, 13(1), 33-33 (2014-03-08)
The industrially applied filamentous fungus Trichoderma reesei has received substantial interest due to its highly efficient synthesis apparatus of cellulytic enzymes. However, the production of heterologous enzymes in T. reesei still remains low mainly due to lack of tools for
Sandeep Kondakala et al.
Toxicology and applied pharmacology, 337, 67-75 (2017-11-04)
The prevalence of obesity is increasing at an alarming rate in the United States with 36.5% of adults being classified as obese. Compared to normal individuals, obese individuals have noted pathophysiological alterations which may alter the toxicokinetics of xenobiotics and
George E Howell et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 118, 821-829 (2018-06-24)
The effects of obesity on organophosphate pesticide-mediated toxicities, including both cholinergic and non-cholinergic targets, have not been fully elucidated. Therefore, the present study was designed to determine if high fat diet intake alters the effects of repeated exposure to chlorpyrifos
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