I1637

Ipratropiumbromid Monohydrat

≥98% (TLC), powder

• Synonym(e): N-(2-Propyl)-atropiniumbromid
• Empirische Formel (Hill-System): C₂₀H₃₀BrNO₃ · H₂O
• CAS-Nummer: 66985-17-9
• Molekulargewicht: 430.38
• EG-Nummer: 244-873-8
• MDL-Nummer: MFCD00792907
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277843
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (TLC)
• Form: powder
• Farbe: white
• Löslichkeit: H₂O: 10 mg/mL
• Ersteller: Boehringer Ingelheim
• SMILES String: O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18+,19?,21?;;
• InChIKey: KEWHKYJURDBRMN-XSAPEOHZSA-M
• Angaben zum Gen: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

Beschreibung

Anwendung

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

Biochem./physiol. Wirkung

Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β₂ adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.

Leistungsmerkmale und Vorteile

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sonstige Hinweise

N-isopropyl quaternary salt of atropine.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H332,H319
• P-Sätze: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2