G4923

(E)-Guggulsteron

≥95% (HPLC), powder

• Synonym(e): (17E)-Pregna-4,17(20)-dien-3,16-dion
• Empirische Formel (Hill-System): C₂₁H₂₈O₂
• CAS-Nummer: 39025-24-6
• Molekulargewicht: 312.45
• MDL-Nummer: MFCD01310758
• UNSPSC-Code: 12352205
• PubChem Substanz-ID: 329799934
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: white to off-white
• Löslichkeit: DMSO: soluble 5 mg/mL
• Funktionelle Gruppe: ketone
• Versandbedingung: ambient
• Lagertemp.: 2-8°C
• SMILES String: C\C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
• InChIKey: WDXRGPWQVHZTQJ-AUKWTSKRSA-N

Beschreibung

Biochem./physiol. Wirkung

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H335,H412
• P-Sätze: P261 - P271 - P273 - P304 + P340 + P312 - P403 + P233 - P405
• Gefahreneinstufungen: Aquatic Chronic 3 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable