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Key Documents

231R-1

Sigma-Aldrich

Calponin-1 (EP798Y) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC-Code:
12352200
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

EP798Y, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (231R-14)
vial of 0.5 mL concentrate (231R-15)
bottle of 1.0 mL predilute (231R-17)
vial of 1.0 mL concentrate (231R-16)
bottle of 7.0 mL predilute (231R-18)

Hersteller/Markenname

Cell Marque™

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotyp

IgG

Kontrolle

appendix

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Verwandte Kategorien

Allgemeine Beschreibung

Calponin is a 34-kD polypeptide that interacts with actin, tropomyosin, and calmodulin. Itis involved in the smooth muscle contraction mechanism and is restricted exclusively to smoothmuscle tissue. Anti-calponin has been found to be useful in staining myoepithelium and thushas been used to confirm the presence of myoepithelial cells in benign breast proliferationand their absence in invasive breast carcinomas. Calponin positivity has also been noted inmyoepithelial neoplasms and pleomorphic adenoma of the salivary gland.

Qualität


IVD
IVD
IVD
RUO

Verlinkung

Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Antibodies to novel myoepithelium-associated proteins distinguish benign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, et al.
Appl. Immunohistochem., 5, 141-151 (1997)
Cheryl B Hill et al.
American journal of clinical pathology, 123(1), 36-44 (2005-03-15)
We evaluated 25 intraductal papillomas and 18 papillary carcinomas (invasive, 4; micropapillary ductal carcinoma in situ [DCIS], 5; cases originally classified as intracystic/intraductal papillary carcinoma, 9) by calponin, smooth muscle myosin heavy chain (SMM-HC), and p63 immunostains. Calponin, SMM-HC, and
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors
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