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317802

4-(4-Isothiocyanatophenylazo)-N,N-dimethylanilin

Name: 4-(4-Isothiocyanatophenylazo)-N,N-dimethylanilin
Brand: SIAL

97%

Synonym(e):

4-Dimethylamino-azobenzol-4′-isothiocyanat, DABITC

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About This Item

Lineare Formel:

SCNC₆H₄N=NC₆H₄N(CH₃)₂

CAS-Nummer:

7612-98-8

Molekulargewicht:

282.36

Beilstein:

752568

EG-Nummer:

231-521-3

MDL-Nummer:

MFCD00004812

UNSPSC-Code:

12171500

PubChem Substanz-ID:

24859100

NACRES:

NA.47

Assay

97%

Form

crystals

mp (Schmelzpunkt)

167-171 °C (lit.)

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)N=C=S

InChI

1S/C15H14N4S/c1-19(2)15-9-7-14(8-10-15)18-17-13-5-3-12(4-6-13)16-11-20/h3-10H,1-2H3/b18-17+

InChIKey

OSWZKAVBSQAVFI-ISLYRVAYSA-N

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Piktogramme

GHS08

Signalwort

Danger

H-Sätze

H317,H334

P-Sätze

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number

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Sigma-Aldrich

8.51022

Dabcyl-OSu

Supelco

46130

4-Aminoazobenzol

Sigma-Aldrich

39068

4-(4-Dimethylaminophenylazo)-benzolsulfonylchlorid

Identification of a reactive lysyl residue (Lys103) of recombinant human interleukin-1 beta. Mechanism of its reactivity and implication of its functional role in receptor binding.

J Y Chang et al.

Biochemistry, 31(11), 2874-2878 (1992-03-24)

Recombinant human interleukin-1 beta (h-IL-1 beta) was chemically modified with 4-(N,N-dimethylamino)-4'-isothiocyanatoazobenzene-2'-sulfonic acid (S-DABITC), a water-soluble color reagent specific for lysine labeling. Modified h-IL-1 beta was digested by lysyl endopeptidase. Peptides containing labeled lysines were detected at the visible wavelength (436

Chemical modification of the Ca(2+)-ATPase of rabbit skeletal muscle sarcoplasmic reticulum: identification of sites labeled with aryl isothiocyanates and thiol-directed conformational probes.

A Wawrzynów et al.

Biochimica et biophysica acta, 1203(1), 60-70 (1993-11-10)

The Ca(2+)-ATPase protein of rabbit skeletal muscle sarcoplasmic reticulum is a single polypeptide chain of 1001 amino-acid residues. Among these residues are 24 Cys, 9 of which have previously been shown to be accessible to one or more thiol-specific reagents.

Ferredoxin binding site on ferredoxin: NADP+ reductase. Differential chemical modification of free and ferredoxin-bound enzyme.

I Jelesarov et al.

European journal of biochemistry, 216(1), 57-66 (1993-08-15)

The chloroplast enzyme ferredoxin: NADP+ reductase (FNR) catalyzes the reduction of NADP+ by ferredoxin (Fd). FNR and Fd form a 1:1 complex that is stabilized by electrostatic interactions between acidic residues of Fd and basic residues of FNR. To localize

Mapping the heparin-binding site of mucus proteinase inhibitor.

P Mellet et al.

Biochemistry, 34(8), 2645-2652 (1995-02-28)

Heparin accelerates the inhibition of neutrophil elastase by mucus proteinase inhibitor (MPI), the physiological antielastase of airways as a result of its binding with the inhibitor [Faller, B., Mély, Y., Gérard, D., & Bieth, J. G. (1992) Biochemistry 31, 8285-8290].

[Analysis of heptaminol in pharmaceutic preparations by liquid chromatography following derivatization with 4-N,N-dimethylaminoazobenzene-4-isothiocyanate].

M Bauer et al.

Journal of chromatography, 292(2), 468-472 (1984-06-01)

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