211842

Brillantschwarz BN

Dye content 60 %

• Synonym(e): Food Black 1
• Empirische Formel (Hill-System): C₂₈H₁₇N₅Na₄O₁₄S₄
• CAS-Nummer: 2519-30-4
• Molekulargewicht: 867.68
• Farbindexnummer: 28440
• EG-Nummer: 219-746-5
• MDL-Nummer: MFCD00078980
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24852710
• NACRES: NA.47

Eigenschaften

• Form: powder
• Qualitätsniveau: 200
• Zusammensetzung: Dye content, 60%
• λmax: 407 nm (2nd); 570 nm
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [Na+].[Na+].[Na+].[Na+].CC(=O)Nc1ccc(c2cc(c(\N=N\c3ccc(\N=N/c4ccc(cc4)S([O-])(=O)=O)c5ccc(cc35)S([O-])(=O)=O)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O
• InChI: 1S/C28H21N5O14S4.4Na/c1-14(34)29-23-10-11-24(50(42,43)44)20-13-25(51(45,46)47)27(28(35)26(20)23)33-32-22-9-8-21(18-7-6-17(12-19(18)22)49(39,40)41)31-30-15-2-4-16(5-3-15)48(36,37)38;;;;/h2-13,35H,1H3,(H,29,34)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47);;;;/q;4*+1/p-4/b31-30-,33-32+;;;;
• InChIKey: GMMAPXRGRVJYJY-OXYXOBGMSA-J

Beschreibung

Anwendung

Brilliant Black BN has been used:

• in micronucleus and comet assays to evaluate its genotoxic effect.
• as a quenching agent in calcium mobilization assay.
• as a redox indicator in microbiological inhibition bioassay using Bacillus megaterium to detect tetracycline and macrolides in milk.

Biochem./physiol. Wirkung

[4-acetamido-5-hydroxy-6-[7-sulfonato-4-(4-sulfonatophenylazo)-1-naphtylazo], also known as food black 1, belongs to the group of azo dyes. Brilliant Black BN is widely used as a food dye and pharmaceutical excipient. In addition, it also acts as an allosteric modulator of the adenosine A1 and A3 receptors and is generally used within calcium mobilization assays to reduce extracellular fluorescence.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)