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199508

Sigma-Aldrich

Acridingelb G

Dye content 90 %

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About This Item

Empirische Formel (Hill-System):
C15H15N3 · HCl
CAS-Nummer:
135-49-9
Molekulargewicht:
273.76
Farbindexnummer:
46025
EG-Nummer:
205-194-2
MDL-Nummer:
MFCD00012661
UNSPSC-Code:
12171500
PubChem Substanz-ID:
24851921
NACRES:
NA.47

Form

crystalline powder

Qualitätsniveau

100

Zusammensetzung

Dye content, 90%

Löslichkeit

water: 1 mg/mL, clear, yellow to orange

λmax

442 nm

ε (Extinktionskoeffizient)

44000 at 262-268 nm

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

Cl[H].Cc1cc2cc3cc(C)c(N)cc3nc2cc1N

InChI

1S/C15H15N3.ClH/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16;/h3-7H,16-17H2,1-2H3;1H

InChIKey

BGLGAKMTYHWWKW-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.

Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Analysenzertifikate (COA)

Lot/Batch Number
MKCC2837
MKBD9116V
MKBF9403V
MKBF9403
MKBD9116

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T Pérez-Ruíz et al.
Analytical and bioanalytical chemistry, 375(5), 661-665 (2003-03-15)
A flow-injection configuration for the determination of formaldehyde is proposed. The method is based on the enhancing effect of formaldehyde on the oxidation of acridine yellow by bromate in acidic medium. The proposed procedure is simple, inexpensive, sensitive and suitable
Qi Qi et al.
The Journal of biological chemistry, 287(9), 6113-6127 (2012-01-05)
Amplification of the epidermal growth factor receptor (EGFR), frequently expressed as a constitutively active deletion mutant (EGFRvIII), occurs commonly in glioblastoma multiformes (GBM). However, blockade of EGFR is therapeutically disappointing for gliomas with PTEN deletion. To search for small molecules
Ashton acton
Gastrointestinal Hormones?Advances in Research and Application (2012)
Brotati Chakraborty et al.
The journal of physical chemistry. A, 114(51), 13313-13325 (2010-12-04)
Conventional spectroscopic tools such as absorption, fluorescence, and circular dichroism spectroscopy used in the study of photoinduced drug-protein interactions can yield useful information about ground-state and excited-state phenomena. However, photoinduced electron transfer (PET) may be a possible phenomenon in the
A H Uggla
Mutation research, 201(1), 229-239 (1988-09-01)
A comparison has been made between the ability of different acridine compounds to act as sensitizers for visible light (400-700 nm) induced chromosomal aberrations and sister-chromatid exchanges (SCE) in unsynchronized Chinese hamster ovary (CHO) cells. Cells were treated for 20
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