16383
Sennosid D
analytical standard
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About This Item
Qualität
analytical standard
Qualitätsniveau
Assay
≥98.0% (HPLC)
Haltbarkeit
limited shelf life, expiry date on the label
Methode(n)
HPLC: suitable
gas chromatography (GC): suitable
Anwendung(en)
food and beverages
Format
neat
Lagertemp.
2-8°C
SMILES String
OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@H]4c5cccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(CO)cc(O)c8C(=O)c23)[C@H](O)[C@@H](O)[C@@H]1O
Verwandte Kategorien
Allgemeine Beschreibung
Sennoside D is an active constituent of senna which is generally used as a laxative. It belongs to anthranoid family, and is procured from dried leaflets and pods of senna plant.
Anwendung
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Verpackung
Bottomless glass bottle. Contents are inside inserted fused cone.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Analytical studies on the active constituents in crude drugs. IV. Determination of sennosides in senna and formulations by high-performance liquid chromatography.
Chemical & Pharmaceutical Bulletin, 28(2), 406-412 (1980)
Review article: anthranoid laxatives and their potential carcinogenic effects.
Alimentary Pharmacology & Therapeutics, 13(4), 443-452 (1999)
The Journal of pharmacy and pharmacology, 44(12), 973-976 (1992-12-01)
Sennosides A and C directly injected into the caecum of mice showed equal purgative activity. Intracaecal administration reduced time to onset of diarrhoea induced by sennoside C from about 3 h after oral administration to about 24 min. At 2.3
Potentiating effect of sennoside C on purgative activity of sennoside A in mice.
Planta medica, 42(3), 302-303 (1981-07-01)
The Journal of pharmacy and pharmacology, 49(1), 22-25 (1997-01-01)
This study aimed to explore the mechanism involved in the synergistic purgative action of aloe-emodin anthrone and rhein anthrone, the active metabolites of sennoside C. Aloe-emodin anthrone and rhein anthrone, and their equimolar mixture, induced excretion of an approximately equal
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