523350

PTIO

Nitric oxide radical scavenger.

• Synonym(e): PTIO, 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide
• Empirische Formel (Hill-System): C₁₃H₁₇N₂O₂
• CAS-Nummer: 18390-00-6
• Molekulargewicht: 233.29
• MDL-Nummer: MFCD00059929
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (titration)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Farbe: dark blue
• Löslichkeit: ethanol: soluble; water: soluble
• Versandbedingung: ambient
• Lagertemp.: −20°C
• InChI: 1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
• InChIKey: DYUUGILMVYJEHY-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner, without affecting nitric oxide synthase activity. Inhibits enhanced vascular permeability in solid tumors.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Nitric oxide radical scavenger

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Irritant (B)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.

Sonstige Hinweise

Hogg, N., et al. 1995. Free Radic. Res. 22, 47.
Maeda, H., et al. 1994. Jpn. J. Cancer Res.85, 331.
Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.
Akaike, T., et al. 1993. Biochemistry32, 827.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable