07-326
Anti-phospho-Cofilin 2 (Ser3) Antibody
Upstate®, from rabbit
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
mouse, chicken, human
Hersteller/Markenname
Upstate®
Methode(n)
western blot: suitable
Isotyp
IgG
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
phosphorylation (pSer3)
Angaben zum Gen
human ... CFL2(1073)
Spezifität
phospho-Cofilin 2
Immunogen
peptide corresponding to amino acids 1-10 (MA[pS]GVTVNDE-C) of human phospho-Cofilin 2
Anwendung
Research Category
Zellstruktur
Zellstruktur
Research Sub Category
Cytoskelett
Cytoskelett
Anti-phospho-Cofilin 2 (Ser3) Antibody detects level of phospho-Cofilin 2 (Ser3) & has been published & validated for use in WB.
Qualität
routinely evaluated by immunoblot on RIPA lysates from L6 cells, treated with LIM Kinase
Zielbeschreibung
21kDa
Physikalische Form
Protein A chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Lagerung und Haltbarkeit
2 years at -20°C
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
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C Thirion et al.
European journal of biochemistry, 268(12), 3473-3482 (2001-06-26)
Cofilins are actin binding proteins and regulate actin assembly in vivo. Numerous cofilin homologues have been characterized in various organisms including mammals. In mice, a ubiquitously expressed cofilin (CFL1) and a skeletal muscle specific cofilin (CFL2) have been described. In
J Craig Hunter et al.
Journal of molecular and cellular cardiology, 47(6), 810-818 (2009-10-06)
Although nitric oxide (NO) has received extensive attention as an anti-hypertrophic agent the mechanisms underlying its regulation of endothelin-1 (ET-1) have not been fully elucidated. Since RhoA has been identified as an important mediator of cardiac hypertrophy and is inhibited
Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.
Albinsson, S; Nordstrom, I; Sward, K; Hellstrand, P
American Journal of Physiology. Cell Physiology null
Toru Amano et al.
The Journal of biological chemistry, 277(24), 22093-22102 (2002-04-02)
Actin filament dynamics play a critical role in mitosis and cytokinesis. LIM motif-containing protein kinase 1 (LIMK1) regulates actin reorganization by phosphorylating and inactivating cofilin, an actin-depolymerizing and -severing protein. To examine the role of LIMK1 and cofilin during the
Mardjaneh Sadegh Karbalaei et al.
European journal of pharmacology, 689(1-3), 179-185 (2012-05-31)
Caveolae are membrane invaginations present in a variety of cell types. Formation of caveolae depends on caveolins and on the more recently discovered family of proteins known as the cavins. Genetic ablation of caveolin-1 was previously shown to give rise
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
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