“Thinking creatively is at the core of our research…”

Thinking creatively about how to build molecules is at the core of the research we do within the Garg lab. By using new creative strategies, we can think about building complex molecules in a new way that could lead to more efficient or selective routes.

I recently had the opportunity to apply this in a unique setting by developing an alternative route to the nucleobase present in remdesivir, an FDA-approved COVID-19 treatment. We anticipate that our synthetic route will further enable the synthesis of remdesivir and other small molecule therapeutics that possess the nucleobase.

“A lot of people don’t understand that organic synthesis is not a solved field…”

My creative approach to organic synthesis stems from a general curiosity and love for learning. I’ve been fortunate to have found a research group that curates an environment focused on creative problem solving. The open nature of our conversations and support from my advisor and peers powers this creative thinking.

I think a lot of people don’t understand the level of creativity that is involved in organic synthesis and that it is not a solved field. There are a number of outstanding challenges, and to solve them it is critical to keep an open mind. Through this perspective, I’ve been able to make molecules through methods that were once considered unattainable.

FAQ

Q: What kind of mindset do you need to achieve the Next Great Impossible?

A: To solve tough problems, it is important to keep a positive mindset, be open to creativity and always continue to learn and grow.