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XPC

xeroderma pigmentosum, complementation group C

Synonyme:
RAD4, XP3, XPCC
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7508) Summary: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(22591) xeroderma pigmentosum, complementation group C
  • Rat(312560) xeroderma pigmentosum, complementation group C
  • Zebrafish(541386) xeroderma pigmentosum, complementation group C
  • dog(476521) xeroderma pigmentosum, complementation group C
  • chicken(416039) xeroderma pigmentosum, complementation group C
  • domestic cat(101080440) xeroderma pigmentosum, complementation group C
  • Horse(100050424) xeroderma pigmentosum, complementation group C
  • naked mole-rat(101707002) xeroderma pigmentosum, complementation group C
  • Domestic Rabbit(100346279) xeroderma pigmentosum, complementation group C
  • domestic guinea pig(100719007) xeroderma pigmentosum, complementation group C
  • cow(524274) xeroderma pigmentosum, complementation group C
  • sheep(101109650) xeroderma pigmentosum, complementation group C

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-XPC antibody produced in mouse, ,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-XPC (C-terminal) in Kaninchen hergestellte Antikörper, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-XPC antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human XPC,
Spezies
human
MISSION® esiRNA, targeting mouse Xpc,
Spezies
mouse