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SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Synonyme:
NAT1, NET, NET1, SLC6A5
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
4,4′-Diaminodiphenylmethan, ≥97.0% (GC),
Spezies
mouse, rat
Nefazodon -hydrochlorid, ≥98% (HPLC), solid,
Spezies
human
Nefazodon -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Amoxapin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Amoxapin, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Norepinephrine Antibody, serum, Chemicon®,
Speziesreaktivität
human, rat
Anwendung
immunohistochemistry
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-Norepinephrin-Transporter-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Desipramin -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
Desipramine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Debrisoquine sulfate, ,
Spezies
human
Atomoxetin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Maprotiline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SLC6A2,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
Guanethidinmonosulfat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Bretyliumtosylat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Guanethidin-Monosulfat, British Pharmacopoeia (BP) Reference Standard,
Spezies
human